oral suspension meaning
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Take this product by mouth as directed. Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.
There are many brands and forms of acetaminophen available. Read the dosing instructions carefully for each product because the amount of acetaminophen may be different between products. Do not take more acetaminophen than recommended. (See also Warning section.)
If you are giving acetaminophen to a child, be sure you use a product that is meant for children. Use your child’s weight to find the right dose on the product package. If you don’t know your child’s weight, you can use their age.
For suspensions, shake the medication well before each dose. Some liquids do not need to be shaken before use. Follow all directions on the product package. Measure the liquid medication with the provided dose-measuring spoon/dropper/syringe to make sure you have the correct dose. Do not use a household spoon.
How to use Child Suspension
For rapidly-dissolving tablets, chew or allow to dissolve on the tongue, then swallow with or without water. For chewable tablets, chew thoroughly before swallowing.
Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
For effervescent tablets, dissolve the dose in the recommended amount of water, then drink.
Pain medications work best if they are used as the first signs of pain occur. If you wait until the symptoms have worsened, the medication may not work as well.
Do not take this medication for fever for more than 3 days unless directed by your doctor. For adults, do not take this product for pain for more than 10 days (5 days in children) unless directed by your doctor. If the child has a sore throat (especially with high fever, headache, or nausea/vomiting), consult the doctor promptly.
What does oral suspension mean?
This medication is used to treat fungal infections of the mouth. Nystatin is an antifungal that works by stopping the growth of fungus. Nystatin suspension should not be used to treat fungal infections of the blood.
Similarly, what is the difference between oral suspension and oral solution? Oral suspensions are very similar to solutions but the drug particles do not completely dissolve into the solvent. They are, instead, “suspended” in the medium of liquid (1) very much like dust particles suspend in the air.
Also know, what is the meaning of suspension in medicine?
A suspension is a liquid with small pieces of drug. The drug is not complete dissolved in the solution. Whenever you take a suspension, you should always shake (or stir) it so that you receive the right amount of drug every time you take it.
What is the difference between a liquid and a suspension?
In an elixir, the active ingredients are mixed with a liquid, usually a kind of syrup or alcohol, in which they can dissolve. In a suspension, the medicine is mixed with a liquid, usually water, in which it cannot dissolve and therefore remains intact in the form of small particles.
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NYSTATIN ORAL SUSPENSION
What are the possible side effects of Nystatin Oral Suspension?
Nystatin Oral Suspension may cause serious side effects including:
- fast heart rate,
- trouble breathing,
- severe skin reaction,
- fever,
- sore throat,
- swelling in your face or tongue,
- burning in your eyes, and
- skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling
Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of Nystatin Oral Suspension include:
- mouth irritation,
- upset stomach,
- nausea,
- vomiting,
- diarrhea, and
- skin rash
Tell the doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Nystatin Oral Suspension. For more information, ask your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
DESCRIPTION
Nystatin is an antimycotic polyene antibiotic obtained from Streptomyces noursei. Structural formula:
Nystatin Oral Suspension is a cherry-mint flavored suspension for oral administration. It contains 100,000 USP Nystatin Units per mL. Inactive ingredients: alcohol ( ≤ 1% v/v), carboxymethylcellulose sodium, flavor, glycerin, methylparaben, propylparaben, purified water, saccharin sodium, sodium citrate, and sucrose (50% w/v). May also contain citric acid for pH adjustment.
INDICATIONS
Nystatin Oral Suspension is indicated for the treatment of candidiasis in the oral cavity.
DOSAGE AND ADMINISTRATION
Infants: 2 mL (200,000 units) four times daily (in infants and young children, use dropper to place one-half of dose in each side of mouth and avoid feeding for 5 to 10 minutes). NOTE: Limited clinical studies in premature and low birth weight infants indicate that 1 mL four times daily is effective.
Children and Adults: 4–6 mL (400,000 to 600,000 units) four times daily (one-half of dose in each side of mouth). The preparation should be retained in the mouth as long as possible before swallowing.
Continue treatment for at least 48 hours after perioral symptoms have disappeared and cultures demonstrate eradication of Candida albicans.
HOW SUPPLIED
Nystatin Oral Suspension, USP, 100,000 USP Nystatin Units per mL, is available as a cherry-mint flavored, light creamy yellow, ready-to-use suspension in 60 mL bottles with calibrated dropper and 473 mL bottles.
PRECAUTIONS
General
This medication is not to be used for the treatment of systemic mycoses.
Discontinue treatment if sensitization or irritation is reported during use.
Carcinogenesis, Mutagenesis, Impairment Of Fertility
No long-term animal studies have been performed to evaluate carcinogenic potential. There also have been no studies to determine mutagenicity or whether this medication affects fertility in males or females.
Pregnancy
Teratogenic Effects – Category C
Animal reproduction studies have not been conducted with nystatin oral suspension. It is also not known whether nystatin oral suspension can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Nystatin oral suspension should be given to a pregnant woman only if clearly needed.
Nursing Mothers
It is not known whether nystatin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when nystatin is administered to a nursing woman.
CLINICAL PHARMACOLOGY
Pharmacokinetics
Gastrointestinal absorption of nystatin is insignificant. Most orally administered nystatin is passed unchanged in the stool. In patients with renal insufficiency receiving oral therapy with conventional dosage forms, significant plasma concentrations of nystatin may occasionally occur.
Microbiology
Nystatin is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi. Candida albicans demonstrates no significant resistance to nystatin in vitro on repeated subculture in increasing levels of nystatin; other Candida species become quite resistant. Generally, resistance does not develop in vivo. Nystatin acts by binding to sterols in the cell membrane of susceptible Candida species with a resultant change in membrane permeability allowing leakage of intracellular components. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
