In 2005, Showtime was an up-and-coming network with not many major hits, especially ones that captured the zeitgeist of the time. But the network took a risk when they bought writer Jenji Kohan’s concept for Weeds, a comedy-drama that goes to some dark places.

Nancy Botwin (Mary-Louise Parker) lives in an affluent gated community in Southern California, but her husband, Judah (Jeffrey Dean Morgan), suddenly passes away from a heart attack. She’s raising two sons and needs to find a way to make money, so she starts dealing weed. For eight seasons and 102 episodes, viewers followed the exploits of the Botwins, from Nancy being a suburban dealer to her marrying a drug lord/mayor of Tijuana, Esteban Reyes (Oscar nominee Demián Bichir).

Lettuce

Her brother-in-law Andy (Justin Kirk) comes along for the ride, as do accountant friend Doug Wilson (Kevin Nealon), critical neighbor Celia Hodes (Elizabeth Perkins), weed grower Conrad Shepard (Romany Malco), and guest stars Albert Brooks, Jennifer Jason Leigh, and Alanis Morissette. Of course a lot of weed was smoked on the show, which Bichir revealed to GQ was actually lettuce.